This home was built in 1880 for Dr. Henry Cowie, a prominent dentist in Detroit.

Cowie's sister, Agnes, married Dr. Henry A. Cleland, a physician, and lived next door at number 702. Cowie's office was in the Detroit Opera House Building until he built his own office building on Gratiot Avenue in the late 1880s.

Cowie lived at this address until the 1920s.